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A source for healthcare professionals to access the latest data and information on the diagnosis, treatment and management of patients with gut related disorders
Professor David S. Sanders
Consultant Gastroenterologist and Professor, Royal Hallamshire Hospital and the University of Sheffield, Sheffield, UK
It has been reported that at least 1 in every 20 individuals in the UK experiences irritable bowel syndrome-type symptoms or chronic diarrhoea.
Of these, how many are suspected to have bile acid diarrhoea?
In my opinion, 1% of the general population has bile acid diarrhoea (BAD) also known as bile acid malabsorption (BAM).
Irritable bowel syndrome (IBS)-type symptoms and chronic diarrhoea are almost interchangeable from the patient’s point of view. I can state that at least 5% of the population (or in other words, 1 in every 20 individuals) will present these symptoms.
If we study these patients systematically, evaluating the symptoms of IBS or chronic diarrhoea, what we will observe will be consistent with the retrospective and prospective studies that indicate that 25% or more of these patients have BAM or BAD.
So you can see how the maths aligns with my statement that I think 1% of the general population have BAD.
Job number: JB57410GBm Date of Preparation: June 2019
Brief report: length of ileal resection correlates with severity of bile acid malabsorption in Crohn’s disease
In patients with Crohn’s disease who had a prior surgical resection there was a modest correlation between the length of ileal resection and the severity of bile acid malabsorption (BAM), as defined by tauroselcholic (75selenium) acid (SeHCAT) retention values. Response to bile salt sequestrant therapy was not dependent on SeHCAT retention values.
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