A source for healthcare professionals to access the latest data and information on the diagnosis, treatment and management of patients with gut related disorders


Expert opinion

Professor Julian R.F. Walters 

Consultant Gastroenterologist and Professor of Gastroenterology, Imperial College London, London, UK

Are the current treatments for bile acid diarrhoea (BAD) effective, and is it likely that in the future there will be better treatments for BAD?


Current therapies, such as colestyramine and colesevelam, bind and eliminate bile acids from the colon. These drugs prevent the excess bile acids causing watery faeces.

Further evidence suggests that the primary defect is due to excess bile acid production, caused by reduced production of FGF19. Therapy to stimulate FGF19, thereby reducing excess bile acids, has been shown in a proof-of-concept study to improve patients’ symptoms.

Job number: JB57410GBl Date of Preparation: June 2019

Are you a healthcare professional?

This educational website is developed by GE Healthcare for educational purposes. The information contained within this website is intended for healthcare professionals. By entering this website you are confirming that you are a healthcare professional.

Enter the website

This link opens another website that is not under the review or control of GE Healthcare Ltd and, as such, the company does not endorse the content, its accuracy, or any practices or standards contained within it.