Prevalence of irritable bowel syndrome-type symptoms in patients with celiac disease: a meta-analysis

Sainsbury A, Sanders D & Ford A. Clin Gastroenterol Hepatol 2013;11:359–365.

Short summary

A high proportion of patients with coeliac disease (CD) experience symptoms similar to irritable bowel syndrome (IBS). 

Using data from cross-sectional surveys and case-control studies, the pooled prevalence of symptoms meeting the criteria for IBS in all patients with CD was 38% (95% CI, 27.0%–50.0%). Prevalence in individual studies varied from 20.0% to 58.4%, with statistically significant heterogeneity between studies (p<0.001). 

Using data from case-control studies, including 626 patients with CD and 1,995 controls without CD, the pooled odds ratio (OR) for IBS-type symptoms was significantly higher in those with patients with CD compared with controls (5.60; 95% CI, 3.23–9.70). All studies included in the meta-analysis included adherence to a gluten-free diet (GFD); adherence ranged from...

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Job number: JB57410GBr(1) Date of Preparation: June 2020

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irritable bowel syndrome celiac disease meta-analysis coeliac disease (cd) gluten-free diet (gfd) ibs-type symptoms in cd professor david s. sanders

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Irritable bowel syndrome (IBS) patient information sheet (English)

Irritable bowel syndrome (IBS) patient information sheet (English)

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