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Irritable bowel syndrome (IBS) is a disorder of exclusion: An extensive diagnostic work-up is necessary

Professor David S. Sanders 

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What is the overall benefit for clinicians of an early diagnosis of bile acid diarrhoea?

The benefit is quite significant, both for the physician and for the patient. For physicians, it provides the possibility to avoid numerous diagnostic tests.

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Diagnosis and management of functional symptoms in inflammatory bowel disease in remission

Teruel C et al. World J Gastrointest Pharmacol Ther 2016;7:78–90.

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Bowel disorders

Lacey B et al. Gastroenterology 2016;150:1393–1407.

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Diagnosis and management of inflammatory bowel disease

Nightingale A. Nurse Prescribing 2007;5:289–296.

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High prevalence of idiopathic bile acid diarrhoea among patients with diarrhoea-predominant irritable bowel syndrome based on Rome III criteria

Aziz, I, Mumtaz S, Bholah H et al. Clin Gastroenterol Hepatol 2015;13:1650–1655.

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Bile acid disease: the emerging epidemic 

Oduyebo I & Camilleri M. Curr Opin Gastroenterol 2017;33:189–195.

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Length of ileal resection correlates with severity of bile acid malabsorption in Crohn’s disease 

Skouras T et al. Int J Colorectal Dis2018; doi:10.1007/s00384-018-3144-1.

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Is bile acid diarrhoea underdiagnosed in patients with Crohn’s disease?

Definitely, yes. Unfortunately for patients with Crohn’s disease, there is a poor relationship between their symptoms and intestinal inflammation, and a considerable proportion of patients’ present symptoms that are not due to the inflammation but rather to bile acid diarrhoea. 

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Inflammatory bowel disease: clinical aspects and treatments

Fakhoury M et al. J Inflamm Res 2014;7:113–120.

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Symptoms of irritable bowel syndrome

Symptoms in this patient point towards a diagnosis of irritable bowel syndrome (IBS)IBS is characterised by the presence of recurring abdominal pain linked to changes in the pattern of bowel movements, be it constipation, diarrhoea, or both.

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Challenging current views on bile acid diarrhoea and malabsorption

Guidance for the use of tauroselcholic (75selenium) acid (SeHCAT) for the investigation of diarrhoea due to bile acid malabsorption (BAM)...

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Welcome to GutNEWS.org

A web hub focussed on providing gastroenterologists with the latest information on the diagnosis, treatment and management of patients with gut related disorders.

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How common is bile acid diarrhoea (BAD)?
Professor David S. Sanders 

How common is bile acid diarrhoea (BAD)?
Professor David S. Sanders 

Professor Sanders argues that many patients presenting with irritable bowel syndrome (IBS) have underlying diseases. He explores a series of studies that suggest approximately 25% of patients presenting with IBS symptoms have BAD as the underlying cause. 

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